Oxycodone Overview

Oxycodone helps treat pain.Pain treatment is one of the most researched fields in medicine. There are hundreds, if not thousands of pain treatments available, ranging from minor cut ointments to injection catalyst for severe pain, such as migraine headache. The short answer is, people do not like to be in pain, and in 1916 a German chemist developed oxycodone which remains the main active-ingredient used in today’s most powerful pain medications.

Oxycodone History

German chemist, Freund and Speyer, were the first to synthesize oxycodone from thebaine in 1916. The development of the drug was intended to replace heroin and morphine because of its harmful dependence. The drug has the same powerful effects as heroin and morphine, however it doesn’t last as long, thus lowering addict statistics.

  • 1917 – first record of clinical use
  • 1939 – first introduced to the US

Oxycodone Forms

Oxycodone can be used with many different binders to tailor treatment according to the patients needs. Here are their forms:

  • OxyContin: Time released (TR); Most popular, it is the most sought after form for abusers, known as Hillbilly Heroin, OC and Killers.
  • Roxicodone: Instant released (IR)
  • Proladone: Suppository (Australia)
  • Eukodol and Eucodol: Injectable oxycodone hydrochloride or tartrate (Europe)
    • Acetaminophen binder: Perocet, Endocet, Tylox, Roxicet
    • Aspirin binder: Percodan, Endodan, Roxiprin
    • Ibuprofen binder: Combunox

Pharmacology of Oxycodone

  • Oral absorption of oxycodone: In rapid release form, such as Roxicodone, oxycodone takes full effect in approximately one hour. In extended release form such as OxyContin, oxycodone will take full effect in approximately three hours.
  • Distribution of oxycodone: Oxycodone is distributed in the blood throughout the entire body. Because pain is the problem, IR form fortunately will take effect within 10 to15 minutes. Time released will start to reduce pain in about an hour.
  • Metabolism of oxycodone: Although oxycodone is similar to morphine and heroin, it metabolizes the cytochrome P450 enzyme differently in the liver. As a result there can be many drug interferences.
  • Elimination of oxycodone: After the drug has metabolized it is excreted through urination or sweat.
  • Dispensation of oxycodone: Oxycodone can be administered through injection, rectally or orally. Over 60 percent prescribed forms of oxycodone are through oral administration.

Side Effects of Oxycodone

Side effects when properly used:

  • Dry mouth
  • Fatigue
  • Nausea
  • Constipation
  • Dizziness
  • Euphoria
  • Lightheaded
  • Diaphoresis
  • Pruritus

Side effects of abuse and overdose:

  • Bradycardia
  • Shallow breathing
  • Apnea
  • Miosis
  • Hyportension
  • Circulatory collapse
  • Respiratory arrest
  • Death

Abuse of Oxycodone

Long-term use of oxycodone can come with severe withdrawal symptoms, especially if the user quits taking the meds abruptly, particularly in the case of abusers. The symptoms are much like any opiate-based drug such as:

  • Insomnia
  • Anxiety
  • Muscle pain
  • Flu symptoms
  • Fever
  • Muscle weakness
  • Nausea

Oxycodone Addiction Treatment

Oxycodone is one of the most widespread, addictive and readily available drugs today. Regular use results in physical and psychological damage and dependence.

There are thousands of people that have used, gone through treatment, and now live normal, healthy lives. If you or someone you know is a oxycodone user, i.e. Oxycotton, Killers and OC, most likely they are already an addict or are quickly becoming one.

There is hope… Please call our toll free number today at (888) 371-5715. We are available 24 hours a day to answer any questions you might have about oxycodone addiction treatment. We are here to help.